Germline Missense Changes in the APC Gene and Their Relationship to Disease

Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of adenomas that carpet the entire colon and rectum. Nonsense and frameshift mutations in the adenomatous polyposis coli (APC) gene account for the majority of mutations identified to date and predispose p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Scott, Rodney J, Crooks, Renee, Rose, Lindy, Attia, John, Thakkinstian, Ammarin, Thomas, Lesley, Spigelman, Allan D, Meldrum, Cliff J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839999/
https://ncbi.nlm.nih.gov/pubmed/20233475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-2-2-81
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge