Automated screening of monoclonal antibodies for SISCAPA assays using a magnetic bead processor and liquid chromatography-selected reaction monitoring-mass spectrometry

Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA) utilizes antibodies to enrich peptides from complex matrices for quantitation by stable isotope dilution mass spectrometry. SISCAPA improves sensitivity and limits the sample handling required for plasma-based analysis. Thus f...

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Hauptverfasser: Schoenherr, Regine M., Zhao, Lei, Whiteaker, Jeffrey R., Feng, Li-Chia, Li, Li, Liu, Lina, Liu, Xiuwen, Paulovich, Amanda G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839902/
https://ncbi.nlm.nih.gov/pubmed/19961853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.11.017
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