Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer

We conducted a two-stage genome-wide association study (GWAS) of pancreatic cancer, a cancer with one of the poorest survival rates worldwide. Initially, we genotyped 558,542 single nucleotide polymorphisms in 1,896 incident cases and 1,939 controls drawn from twelve prospective cohorts plus one hos...

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Main Authors: Amundadottir, Laufey, Kraft, Peter, Stolzenberg-Solomon, Rachael Z., Fuchs, Charles S., Petersen, Gloria M., Arslan, Alan A., Bueno-de-Mesquita, H. Bas, Gross, Myron, Helzlsouer, Kathy, Jacobs, Eric J., LaCroix, Andrea, Zheng, Wei, Albanes, Demetrius, Bamlet, William, Berg, Christine D., Berrino, Franco, Bingham, Sheila, Buring, Julie E., Bracci, Paige M., Canzian, Federico, Clavel-Chapelon, Françoise, Clipp, Sandra, Cotterchio, Michelle, de Andrade, Mariza, Duell, Eric J., Fox, John W., Gallinger, Steven, Gaziano, J. Michael, Giovannucci, Edward L., Goggins, Michael, González, Carlos A., Hallmans, Göran, Hankinson, Susan E., Hassan, Manal, Holly, Elizabeth A., Hunter, David J., Hutchinson, Amy, Jackson, Rebecca, Jacobs, Kevin B., Jenab, Mazda, Kaaks, Rudolf, Klein, Alison P., Kooperberg, Charles, Kurtz, Robert C., Li, Donghui, Lynch, Shannon M., Mandelson, Margaret, McWilliams, Robert R., Mendelsohn, Julie B., Michaud, Dominique S., Olson, Sara H., Overvad, Kim, Patel, Alpa V., Peeters, Petra H.M., Rajkovic, Aleksandar, Riboli, Elio, Risch, Harvey A., Shu, Xiao-Ou, Thomas, Gilles, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Van Den Eeden, Stephen K., Virtamo, Jarmo, Wactawski-Wende, Jean, Wolpin, Brian M., Yu, Herbert, Yu, Kai, Zeleniuch-Jacquotte, Anne, Chanock, Stephen J., Hartge, Patricia, Hoover, Robert N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839871/
https://ncbi.nlm.nih.gov/pubmed/19648918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.429
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