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Antiviral activity of antilipidemic compounds on herpes simplex virus type 1.

Two antilipidemic compounds, clofibrate and procetofene, inhibited the replication of herpes simplex virus type 1 (HSV-1) in African green monkey kidney cells. Clofibrate, at a concentration of 400 mumol/liter caused a 63% reduction (P < 0.001) in HSV-1 yield and at 100 mumol/liter caused a 62% redu...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Mehl, J K, Witiak, D T, Hamparian, V V, Hughes, J H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.2.269
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