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Gene transfer of Fas ligand induces tumor regression in vivo

The Fas–Fas ligand (FasL) system plays an important role in the induction of lymphoid apoptosis and has been implicated in the suppression of immune responses. Herein, we report that gene transfer of FasL inhibits tumor cell growth in vivo. Although such inhibition is expected in Fas(+) tumor cell l...

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Détails bibliographiques
Auteurs principaux: Arai, Hiroshi, Gordon, David, Nabel, Elizabeth G., Nabel, Gary J.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC28398/
https://ncbi.nlm.nih.gov/pubmed/9391118
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