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Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

[Image: see text] NADPH oxidase 4 (Nox4) is constitutively active, while Nox2 requires the cytosolic regulatory subunits p47(phox) and p67(phox) and activated Rac with activation by phorbol 12-myristate 13-acetate (PMA). This study was undertaken to identify the domain on Nox4 that confers constitut...

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Detalhes bibliográficos
Main Authors: Nisimoto, Yukio, Jackson, Heather M., Ogawa, Hisamitsu, Kawahara, Tsukasa, Lambeth, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839512/
https://ncbi.nlm.nih.gov/pubmed/20163138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9022285
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