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Extracellular Signal-Regulated Kinase Positively Regulates the Oncogenic Activity of MCT-1 in Diffuse Large B-Cell Lymphoma

The MCT-1 oncogene was originally identified from lymphoma cell lines. Herein we establish that MCT-1 is highly expressed in 85% of human diffuse large B-cell lymphomas (DLBCL) and that knocking down MCT-1 by a specific short hairpin RNA in DLBCL cells induces apoptosis, supporting a critical role f...

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Main Authors: Dai, Bojie, Zhao, X. Frank, Hagner, Patrick, Shapiro, Paul, Mazan-Mamczarz, Krystyna, Zhao, Shuchun, Natkunam, Yasodha, Gartenhaus, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839501/
https://ncbi.nlm.nih.gov/pubmed/19789340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1606
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