Inhibition of Tumor Growth and Metastasis by a Combination of Escherichia coli–mediated Cytolytic Therapy and Radiotherapy

We have reported that Escherichia coli K-12 colonizes hypoxic and necrotic tumor regions after intravenous injection into tumor-bearing mice. In this study, we established a novel strategy for cancer therapy using engineered bacteria to enhance the therapeutic effects of radiation. E. coli strain K-...

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Main Authors: Jiang, Sheng-Nan, Phan, Thuy X, Nam, Taek-Keun, Nguyen, Vu H, Kim, Hyung-Seok, Bom, Hee-Seung, Choy, Hyon E, Hong, Yeongjin, Min, Jung-Joon
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839435/
https://ncbi.nlm.nih.gov/pubmed/20051939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.295
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