Immune Responses to AAV in Canine Muscle Monitored by Cellular Assays and Noninvasive Imaging

We previously demonstrated that direct intramuscular injection of rAAV2 or rAAV6 in wild-type dogs resulted in robust T-cell responses to viral capsid proteins, and others have shown that cellular immunity to adeno-associated virus (AAV) capsid proteins coincided with liver toxicity and elimination...

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Detalhes bibliográficos
Main Authors: Wang, Zejing, Storb, Rainer, Lee, Donghoon, Kushmerick, Martin J, Chu, Baocheng, Berger, Carolina, Arnett, Andrea, Allen, James, Chamberlain, Jeffrey S, Riddell, Stanley R, Tapscott, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839426/
https://ncbi.nlm.nih.gov/pubmed/20040912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.294
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