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Historical Constraints on Vertebrate Genome Evolution

Recent analyses indicated that genes with larger effect of knockout or mutation and with larger probability to revert to single copy after whole genome duplication are expressed earlier in development. Here, we further investigate whether tissue specificity of gene expression is constrained by the a...

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Bibliographic Details
Main Authors: Milinkovitch, Michel C., Helaers, Raphaël, Tzika, Athanasia C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839353/
https://ncbi.nlm.nih.gov/pubmed/20333219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evp052
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