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Current Issues and Future Directions of Oncolytic Adenoviruses

Oncolytic adenoviruses (Ads) constitute a promising new class of anticancer agent. They are based on the well-studied adenoviral vector system, which lends itself to concept-driven design to generate oncolytic variants. The first oncolytic Ad was approved as a drug in China in 2005, although clinica...

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Detalhes bibliográficos
Main Authors: Yamamoto, Masato, Curiel, David T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839292/
https://ncbi.nlm.nih.gov/pubmed/19935777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.266
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