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The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

BACKGROUND AND PURPOSE: In adults, neurogenesis persists in the hippocampus and the subventricular zone (SVZ), and this is important for learning and memory. Inhibitors of COX-2 suppress ischaemia-induced neurogenesis in the hippocampus. Here, we have determined the effects of COX-2 inhibitors on ne...

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Autori principali: Goncalves, Maria Beatriz, Williams, Emma-Jane, Yip, Ping, Yáñez-Muñoz, Rafael J, Williams, Gareth, Doherty, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839269/
https://ncbi.nlm.nih.gov/pubmed/20136845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00618.x
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