Ligand-directed signalling at β-adrenoceptors

β-Adrenoceptors (ARs) classically mediate responses to the endogenous ligands adrenaline and noradrenaline by coupling to Gsα and stimulating cAMP production; however, drugs designed as β-AR agonists or antagonists can activate alternative cell signalling pathways, with the potential to influence cl...

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Podrobná bibliografie
Hlavní autoři: Evans, Bronwyn A, Sato, Masaaki, Sarwar, Mohsin, Hutchinson, Dana S, Summers, Roger J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Themed Section: Reviews
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839261/
https://ncbi.nlm.nih.gov/pubmed/20132209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00602.x
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