Netrin-1 Mediates Neuronal Survival Through PIKE-L Interaction With the Dependence Receptor UNC5B

Netrins, a family of secreted molecules, play critical roles in axon guidance and cell migration during neuronal development 1,2. In addition to its role as a chemotropic molecule, netrin-1 also acts as a survival factor 3–7. Both UNC5 (i.e. UNC5A, B, C or D) and DCC are transmembrane receptors for...

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Main Authors: Tang, Xiaoling, Jang, Sung-Wuk, Okada, Masashi, Chan, Chi-Bun, Feng, Yue, Liu, Yu, Luo, Shi-Wen, Hong, Yan, Rama, Nicolas, Xiong, Wen-cheng, Mehlen, Patrick, Ye, Keqiang
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839190/
https://ncbi.nlm.nih.gov/pubmed/18469807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1732
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