Hydrolysis of Cefotaxime by a beta-lactamase from Bacteroides fragilis.

A beta-lactamase isolated from a strain of Bacteroides fragilis subsp. fragilis possessed hydrolytic activity toward cefotaxime. This antibiotic was degraded to a lower extent than was cephalothin, cephaloridine, and cefamandole, whereas cefoxitin remained unaffected by the enzyme. Kinetic parameter...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Pechère, J C, Guay, R, Dubois, J, Letarte, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1980
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6250465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.1001
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