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Stimulation of glucose transporter isoform 4 storage vesicle formation by sphingolipid depletion

Insulin stimulates glucose transport in fat and skeletal muscle cells primarily by inducing the translocation of the glucose transporter isoform 4 (GLUT4) to the plasma membrane (PM) from specialized GLUT4 storage vesicles (GSVs). Glycosphingolipids are components of membrane microdomains and are in...

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Autori principali: Cheng, Zhi-Jie, Singh, Raman Deep, Wang, Teng-ke, Holicky, Eileen L., Wheatley, Christine L., Bernlohr, David A., Marks, David L., Pagano, Richard E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838997/
https://ncbi.nlm.nih.gov/pubmed/20085539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091529
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