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Direct quantitation of glucoraphanin in dog and rat plasma by LC-MS/MS

A rapid method to quantify levels of the β-thioglycoside N-hydroxyl sulfate, glucoraphanin, in dog and rat plasma to support pre-clinical toxicological and pharmacological studies has been developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Glucoraphanin was extracted from pla...

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Autors principals: Cwik, Michael J., Wu, Huaping, Muzzio, Miguel, McCormick, David L., Kapetanovic, Izet
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838987/
https://ncbi.nlm.nih.gov/pubmed/20144518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2010.01.020
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