Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing

BACKGROUND: Cancer cells undergo massive alterations to their DNA methylation patterns that result in aberrant gene expression and malignant phenotypes. However, the mechanisms that underlie methylome changes are not well understood nor is the genomic distribution of DNA methylation changes well cha...

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Detaylı Bibliyografya
Asıl Yazarlar: Ruike, Yoshinao, Imanaka, Yukako, Sato, Fumiaki, Shimizu, Kazuharu, Tsujimoto, Gozoh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838848/
https://ncbi.nlm.nih.gov/pubmed/20181289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-137
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