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Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility

BACKGROUND: Ratio-based analysis is the current standard for the analysis of dual-color microarray data. Indeed, this method provides a powerful means to account for potential technical variations such as differences in background signal, spot size and spot concentration. However, current high densi...

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Hlavní autoři: Bossers, Koen, Ylstra, Bauke, Brakenhoff, Ruud H, Smeets, Serge J, Verhaagen, Joost, van de Wiel, Mark A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838842/
https://ncbi.nlm.nih.gov/pubmed/20163706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-112
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