Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R )mice

BACKGROUND: Apert syndrome is characterized by craniosynostosis and limb abnormalities and is primarily caused by FGFR2 +/P253R and +/S252W mutations. The former mutation is present in approximately one third whereas the latter mutation is present in two-thirds of the patients with this condition. W...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yingli, Sun, Miao, Uhlhorn, Victoria L, Zhou, Xueyan, Peter, Inga, Martinez-Abadias, Neus, Hill, Cheryl A, Percival, Christopher J, Richtsmeier, Joan T, Huso, David L, Jabs, Ethylin Wang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838826/
https://ncbi.nlm.nih.gov/pubmed/20175913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-22
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg