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GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

BACKGROUND: Nearly 1% of children in the United States exhibit autism spectrum disorders, but causes and treatments remain to be identified. Mice with deletion of the fragile X mental retardation 1 (Fmr1) gene are used to model autism because loss of Fmr1 gene function causes Fragile X Syndrome (FXS...

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Autori principali: Mines, Marjelo A., Yuskaitis, Christopher J., King, Margaret K., Beurel, Eleonore, Jope, Richard S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838793/
https://ncbi.nlm.nih.gov/pubmed/20300527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009706
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