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A Novel Method of Production and Biophysical Characterization of the Catalytic Domain of Yeast Oligosaccharyl Transferase

Oligosaccharyl transferase (OT) is a multi-subunit enzyme that catalyzes N-linked glycosylation of nascent polypeptides in the lumen of the endoplasmic reticulum. In the case of Saccharomyces cerevisiae, OT is composed of nine integral membrane protein subunits. Defects in N-linked glycosylation cau...

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Autors principals: Huang, Chengdong, Mohanty, Smita, Banerjee, Monimoy
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838725/
https://ncbi.nlm.nih.gov/pubmed/20047336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902181v
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