Mode of action of a new nalidixic acid derivative, AB206.

A new chemotherapeutic agent, AB206, shows potent antibacterial activity against gram-negative bacteria, including most of the nalidixic acid-resistant strains tested. It strongly inhibits deoxyribonucleic acid (DNA) synthesis in Escherichia coli, but only slightly inhibits ribonucleic acid and prot...

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Bibliographic Details
Main Authors: Nagate, T, Komatsu, T, Izawa, A, Ohmura, S, Namiki, S, Mitsuhashi, S
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC283872/
https://ncbi.nlm.nih.gov/pubmed/6156644
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