Transcriptional activation of DNA-dependent protein kinase catalytic subunit gene expression by oestrogen receptor-α

The cellular response to DNA double-strand break (DSB) occurs through an integrated sensing and signalling network that maintains genomic stability. Oestrogen (E2), among its many functions, is known to have a positive effect on global genomic DNA repair; however, the mechanism by which it functions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Medunjanin, Senad, Weinert, Sönke, Poitz, David, Schmeisser, Alexander, Strasser, Ruth H, Braun-Dullaeus, Ruediger C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Scientific Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838685/
https://ncbi.nlm.nih.gov/pubmed/20111054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.279
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