A peripheral neuroimmune link: glutamate agonists upregulate NMDA NR1 receptor mRNA and protein, vimentin, TNF-α, and RANTES in cultured human synoviocytes

Human primary and clonal synovial cells were incubated with glutamate receptor agonists to assess their modulating influence on glutamate receptors N-methyl-d-aspartate (NMDA) NR1 and NR2 and inflammatory cytokines to determine potential for paracrine or autocrine (neurocrine) upregulation of glutam...

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Bibliographic Details
Main Authors: McNearney, Terry A., Ma, Yinghong, Chen, Yueping, Taglialatela, Giulio, Yin, Huaizhi, Zhang, Wen-Ru, Westlund, Karin N.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838657/
https://ncbi.nlm.nih.gov/pubmed/20007519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00452.2009
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