Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia

Vascular calcification is a multifaceted process involving gain of calcification inducers and loss of calcification inhibitors. One such inhibitor is inorganic pyrophosphate (PP(i)), and regulated generation and homeostasis of extracellular PP(i) is a critical determinant of soft-tissue mineralizati...

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Detaylı Bibliyografya
Asıl Yazarlar: Prosdocimo, Domenick A., Wyler, Steven C., Romani, Andrea M., O'Neill, W. Charles, Dubyak, George R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Vascular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838579/
https://ncbi.nlm.nih.gov/pubmed/20018951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00419.2009
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