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p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

Oxidative stress is a primary trigger of cachectic muscle wasting, but the signaling pathway(s) that links it to the muscle wasting processes remains to be defined. Here, we report that activation of p38 mitogen-activated protein kinase (MAPK) (phosphorylation) and increased oxidative stress (trans-...

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Detalhes bibliográficos
Main Authors: McClung, J. M., Judge, A. R., Powers, S. K., Yan, Z.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838571/
https://ncbi.nlm.nih.gov/pubmed/19955483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00192.2009
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