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Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways

Recent studies have implicated Toll-like receptor 2 (TLR2) and TLR4 signaling in delimiting liver and brain injury following ischemia-reperfusion (I/R). To determine whether TLR2 and TLR4 conferred cytoprotection in the heart, we subjected hearts of wild-type (WT) mice and mice deficient in TLR2 (TL...

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Detalhes bibliográficos
Main Authors: Dong, Jian-Wen, Vallejo, Jesus G., Tzeng, Huei-Ping, Thomas, James A, Mann, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838552/
https://ncbi.nlm.nih.gov/pubmed/20061547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00306.2009
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