Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer’s disease

Profound neuronal dysfunction in the entorhinal cortex contributes to early loss of short-term memory in Alzheimer’s disease1–3. Here we show broad neuroprotective effects of entorhinal brain-derived neurotrophic factor (BDNF) administration in several animal models of Alzheimer’s disease, with exte...

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Autori principali: Nagahara, Alan H, Merrill, David A, Coppola, Giovanni, Tsukada, Shingo, Schroeder, Brock E, Shaked, Gideon M, Wang, Ling, Blesch, Armin, Kim, Albert, Conner, James M, Rockenstein, Edward, Chao, Moses V, Koo, Edward H, Geschwind, Daniel, Masliah, Eliezer, Chiba, Andrea A, Tuszynski, Mark H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838375/
https://ncbi.nlm.nih.gov/pubmed/19198615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1912
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