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Effect of protein binding on the penetration of nonmetabolized cephalosporins into atrial appendage and pericardial fluids in open-heart surgical patients.

At various times before surgery, 33 patients undergoing coronary artery bypass or cardiac valve replacement surgery received a single 2.0-g dose of either cefazolin or cephradine. Simultaneous single serum, atrial appendage, and pericardial fluid samples were obtained from the patients at various ti...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Nightingale, C H, Klimek, J J, Quintiliani, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7396452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.4.595
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