Effect of protein binding on the penetration of nonmetabolized cephalosporins into atrial appendage and pericardial fluids in open-heart surgical patients.

At various times before surgery, 33 patients undergoing coronary artery bypass or cardiac valve replacement surgery received a single 2.0-g dose of either cefazolin or cephradine. Simultaneous single serum, atrial appendage, and pericardial fluid samples were obtained from the patients at various ti...

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Bibliographic Details
Main Authors: Nightingale, C H, Klimek, J J, Quintiliani, R
Format: Artigo
Language:Inglês
Published: 1980
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC283837/
https://ncbi.nlm.nih.gov/pubmed/7396452
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