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Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression

Transcription factor Kruppel-like factor 4 (Klf4) is essential for somatic cell reprogramming. In addition, Klf4 seems to play a redundant role along with other Klf family proteins in embryonic stem (ES) cell self-renewal. However, how Klf4 regulates ES cell self-renewal and somatic cell reprogrammi...

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Bibliografske podrobnosti
Main Authors: Zhang, Peilin, Andrianakos, Rose, Yang, Yang, Liu, Chunming, Lu, Wange
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838337/
https://ncbi.nlm.nih.gov/pubmed/20071344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077958
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