Self-assembling SAS-6 Multimer Is a Core Centriole Building Block

Centrioles are conserved microtubule-based organelles with 9-fold symmetry that are essential for cilia and mitotic spindle formation. A conserved structure at the onset of centriole assembly is a “cartwheel” with 9-fold radial symmetry and a central tubule in its core. It remains unclear how the ca...

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Bibliographische Detailangaben
Hauptverfasser: Gopalakrishnan, Jayachandran, Guichard, Paul, Smith, Andrew H., Schwarz, Heinz, Agard, David A., Marco, Sergio, Avidor-Reiss, Tomer
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838298/
https://ncbi.nlm.nih.gov/pubmed/20083610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.092627
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