Chargement en cours...

Stress-sensitive Regulation of IFRD1 mRNA Decay Is Mediated by an Upstream Open Reading Frame

In this report, we demonstrate that cellular stress regulates expression of IFRD1 by a post-transcriptional control mechanism. IFRD1 mRNA and protein are elevated in tunicamycin-treated human kidney epithelial cells via stabilization of the mRNA. IFRD1 mRNA instability in resting cells requires tran...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhao, Chenyang, Datta, Shyamasree, Mandal, Palash, Xu, Shuqing, Hamilton, Thomas
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838277/
https://ncbi.nlm.nih.gov/pubmed/20080976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070920
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!