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Vesicular Stomatitis Virus Genomic RNA Persists In Vivo in the Absence of Viral Replication

Our previous studies using intranasal inoculation of mice with vesicular stomatitis virus (VSV) vaccine vectors showed persistence of vector genomic RNA (gRNA) for at least 60 days in lymph nodes in the absence of detectable infectious virus. Here we show high-level concentration of virus and gRNA i...

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Bibliografische gegevens
Hoofdauteurs: Simon, Ian D., van Rooijen, Nico, Rose, John K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838132/
https://ncbi.nlm.nih.gov/pubmed/20032173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02052-09
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