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Protection against Lethal Vaccinia Virus Challenge by Using an Attenuated Matrix Protein Mutant Vesicular Stomatitis Virus Vaccine Vector Expressing Poxvirus Antigens

Recombinant vesicular stomatitis viruses (VSV) are excellent candidate vectors for vaccination against human diseases. The neurovirulence of VSV in animal models requires the attenuation of the virus for use in humans. Previous efforts have focused on attenuating virus replication. Studies presented...

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Bibliografiske detaljer
Main Authors: Braxton, Cassandra L., Puckett, Shelby H., Mizel, Steven B., Lyles, Douglas S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838111/
https://ncbi.nlm.nih.gov/pubmed/20089648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01572-09
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