Evolutionary Genetics of Human Enterovirus 71: Origin, Population Dynamics, Natural Selection, and Seasonal Periodicity of the VP1 Gene

Human enterovirus 71 (EV-71) is one of the major etiologic causes of hand, foot, and mouth disease (HFMD) among young children worldwide, with fatal instances of neurological complications becoming increasingly common. Global VP1 capsid sequences (n = 628) sampled over 4 decades were collected and s...

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Bibliographic Details
Main Authors: Tee, Kok Keng, Lam, Tommy Tsan-Yuk, Chan, Yoke Fun, Bible, Jon M., Kamarulzaman, Adeeba, Tong, C. Y. William, Takebe, Yutaka, Pybus, Oliver G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Genetic Diversity and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838098/
https://ncbi.nlm.nih.gov/pubmed/20089660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01019-09
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