Dysautonomia Due to Reduced Cholinergic Neurotransmission Causes Cardiac Remodeling and Heart Failure

Overwhelming evidence supports the importance of the sympathetic nervous system in heart failure. In contrast, much less is known about the role of failing cholinergic neurotransmission in cardiac disease. By using a unique genetically modified mouse line with reduced expression of the vesicular ace...

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Autori principali: Lara, Aline, Damasceno, Denis D., Pires, Rita, Gros, Robert, Gomes, Enéas R., Gavioli, Mariana, Lima, Ricardo F., Guimarães, Diogo, Lima, Patricia, Bueno, Carlos Roberto, Vasconcelos, Anilton, Roman-Campos, Danilo, Menezes, Cristiane A. S., Sirvente, Raquel A., Salemi, Vera M., Mady, Charles, Caron, Marc G., Ferreira, Anderson J., Brum, Patricia C., Resende, Rodrigo R., Cruz, Jader S., Gomez, Marcus Vinicius, Prado, Vania F., de Almeida, Alvair P., Prado, Marco A. M., Guatimosim, Silvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838086/
https://ncbi.nlm.nih.gov/pubmed/20123977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00996-09
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