Discrepancy in Dengue Virus Neutralizing Antibody Titers between Plaque Reduction Neutralizing Tests with Fcγ Receptor (FcγR)-Negative and FcγR-Expressing BHK-21 Cells

Protective immunity against dengue virus (DENV) is best reflected by the presence of neutralizing antibodies. The conventional plaque reduction neutralizing test (PRNT) is performed using Fcγ receptor (FcγR)-negative cells. Because FcγR plays a key role in antibody-dependent enhancement, we examined...

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Bibliographic Details
Main Authors: Moi, Meng Ling, Lim, Chang-Kweng, Kotaki, Akira, Takasaki, Tomohiko, Kurane, Ichiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Microbial Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837954/
https://ncbi.nlm.nih.gov/pubmed/20042518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00396-09
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