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Sequence Variation in IGF1R is Associated with Differences in Insulin Levels in Nondiabetic Old Order Amish

BACKGROUND: IGF1R encodes the Insulin-like Growth Factor 1 Receptor, a transmembrane tyrosine kinase receptor located on chromosome 15q26.3, in a region of linkage (LOD=2.53, P=0.00032) to insulin levels at 30 minutes (Insulin30) on an oral glucose tolerance test (OGTT) in the Old Order Amish. Mouse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Naj, Adam C., Kao, Wen-Hong L., O’Connell, Jeffrey R., Mitchell, Braxton D., Silver, Kristi D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837841/
https://ncbi.nlm.nih.gov/pubmed/19877134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.1044
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