NanoART synthesis, characterization, uptake, release and toxicology for human monocyte—macrophage drug delivery

BACKGROUND: Factors limiting the efficacy of conventional antiretroviral therapy for HIV-1 infection include treatment adherence, pharmacokinetics and penetration into viral sanctuaries. These affect the rate of viral mutation and drug resistance. In attempts to bypass such limitations, nanoparticle...

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Autori principali: Nowacek, Ari S, Miller, Reagan L, McMillan, JoEllyn, Kanmogne, Georgette, Kanmogne, Michel, Mosley, R Lee, Ma, Zhiya, Graham, Sabine, Chaubal, Mahesh, Werling, Jane, Rabinow, Barrett, Dou, Huanyu, Gendelman, Howard E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837804/
https://ncbi.nlm.nih.gov/pubmed/19958227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.09.71
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