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cAMP-independent Activation of Protein Kinase A by the Peroxynitrite Generator SIN-1 Elicits Positive Inotropic Effects in Cardiomyocytes

The phosphatase vs. kinase equilibrium plays a critical role in the regulation of myocardial contractility. Previous studies have demonstrated that peroxynitrite exerts a biphasic effect on cardiomyocyte contraction, such that high peroxynitrite reduced β-adrenergic-stimulated myocyte contraction by...

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Bibliografiska uppgifter
Huvudupphovsmän: Kohr, Mark J, Traynham, Christopher J, Roof, Steve R, Davis, Jonathan P, Ziolo, Mark T
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837779/
https://ncbi.nlm.nih.gov/pubmed/20083118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.01.007
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