Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with Major Depressive Disorder - the EMC trial

BACKGROUND: In Major Depressive Disorder (MDD), the traditional belief of a delayed onset of antidepressants' effects has lead to the concept of current guidelines that treatment durations should be between 3-8 weeks before medication change in case of insufficient outcome. Post hoc analyses of...

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Main Authors: Tadić, André, Gorbulev, Stanislav, Dahmen, Norbert, Hiemke, Christoph, Braus, Dieter F, Röschke, Joachim, van Calker, Dietrich, Wachtlin, Daniel, Kronfeld, Kai, Gorbauch, Thorsten, Seibert-Grafe, Monika, Lieb, Klaus
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Study protocol
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837649/
https://ncbi.nlm.nih.gov/pubmed/20187947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-11-21
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