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The IGF1 small dog haplotype is derived from Middle Eastern grey wolves

BACKGROUND: A selective sweep containing the insulin-like growth factor 1 (IGF1) gene is associated with size variation in domestic dogs. Intron 2 of IGF1 contains a SINE element and single nucleotide polymorphism (SNP) found in all small dog breeds that is almost entirely absent from large breeds....

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Bibliographic Details
Main Authors: Gray, Melissa M, Sutter, Nathan B, Ostrander, Elaine A, Wayne, Robert K
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837629/
https://ncbi.nlm.nih.gov/pubmed/20181231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-8-16
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