Motor phenotype of LRRK2 G2019S carriers in Early Onset Parkinson Disease

OBJECTIVE: To determine the motor phenotype of LRRK2 G2019S mutation carriers BACKGROUND: LRRK2 mutation carriers were previously reported to manifest the tremor-dominant (TD) motor phenotype, which has been associated with slower motor progression and less cognitive impairment compared to the postu...

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Autori principali: Alcalay, RN, Mejia-Santana, H, Tang, M-X, Rosado, L, Verbitsky, M, Kisselev, S, Ross, B, Louis, ED, Comella, C, Colcher, A, Jennings, D, Nance, M, Bressman, S, Scott, WK, Tanner, C, Mickel, S, Andrews, H, Waters, C, Fahn, S, Cote, L, Frucht, S, Ford, B, Rezak, M, Novak, K, Friedman, JH, Pfeiffer, R, Marsh, L, Hiner, B, Siderowf, A, Caccappolo, E, Ottman, R, Clark, LN, Marder, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837584/
https://ncbi.nlm.nih.gov/pubmed/20008657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.267
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