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Rational Design of Amyloid Binding Agents Based on the Molecular Rotor Motif

Alzheimer’s disease (AD) is characterized by a progressive loss of cognitive function and constitutes the most common and fatal neurodegenerative disorder.[1] Genetic and clinical evidence supports the hypothesis that accumulation of amyloid deposits in the brain plays an important role in the patho...

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Detalhes bibliográficos
Main Authors: Sutharsan, Jeyanthy, Dakanali, Marianna, Capule, Christina C., Haidekker, Mark A., Yang, Jerry, Theodorakis, Emmanuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837554/
https://ncbi.nlm.nih.gov/pubmed/20024978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900440
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