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Rational Design of Amyloid Binding Agents Based on the Molecular Rotor Motif

Alzheimer’s disease (AD) is characterized by a progressive loss of cognitive function and constitutes the most common and fatal neurodegenerative disorder.[1] Genetic and clinical evidence supports the hypothesis that accumulation of amyloid deposits in the brain plays an important role in the patho...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sutharsan, Jeyanthy, Dakanali, Marianna, Capule, Christina C., Haidekker, Mark A., Yang, Jerry, Theodorakis, Emmanuel A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837554/
https://ncbi.nlm.nih.gov/pubmed/20024978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200900440
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