Isoniazid interaction with tyrosine as a possible mode of action of the drug in mycobacteria.
The antitubercular drug isoniazid (INH) was hown by radio-chromatographic studies to react with tyrosine in growth medium. Exogenous tyrosine added to the growth medium interfered with the inhibitory action of INH on Mycobacterium phlei. These observations were confirmed by difference spectra studie...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7387139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.2.170 |
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