Loading...

The Wilms’ tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells

A switch from estrogen-dependent to estrogen-independent growth is a critical step in malignant progression of breast cancer and is a major problem in endocrine therapy. However, the molecular mechanisms underlying this switch remain poorly understood. The Wilms’ tumor suppressor gene, wt1, encodes...

Full description

Saved in:
Bibliographic Details
Main Authors: WANG, LEI, WANG, ZHAO-YI
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837513/
https://ncbi.nlm.nih.gov/pubmed/20204298
Tags: Add Tag
No Tags, Be the first to tag this record!