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Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell proliferation

Anacardic acid (2-hydroxy-6-alkylbenzoic acid) is a dietary and medicinal phytochemical with established anticancer activity in cell and animal models. The mechanisms by which anacardic acid inhibits cancer cell proliferation remain undefined. Anacardic acid 24:1(ω5) (AnAc 24:1(ω5)) was purified fro...

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Autors principals: Schultz, David J., Wickramasinghe, Nalinie S., Ivanova, Margarita M., Isaacs, Susan M., Dougherty, Susan M., Imbert-Fernandez, Yoannis, Cunningham, Albert R., Chen, Chunyuan, Klinge, Carolyn M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837512/
https://ncbi.nlm.nih.gov/pubmed/20197399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0978
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