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Tissue factor-factor VIIa–specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration

Tissue factor (TF), the cellular receptor for factor VIIa (FVIIa), besides initiating blood coagulation, is believed to play an important role in tissue repair, inflammation, angiogenesis, and tumor metastasis. Like TF, the chemokine interleukin-8 (IL-8) is shown to play a critical role in these pro...

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Detalhes bibliográficos
Main Authors: Hjortoe, Gertrud M., Petersen, Lars C., Albrektsen, Tatjana, Sorensen, Brit B., Norby, Peder L., Mandal, Samir K., Pendurthi, Usha R., Rao, L. Vijaya Mohan
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837482/
https://ncbi.nlm.nih.gov/pubmed/15070680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-10-3417
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