Genes Required for Mitotic Spindle Assembly in Drosophila S2 Cells

The formation of a metaphase spindle, a bipolar microtubule array with centrally aligned chromosomes, is a prerequisite for the faithful segregation of a cell’s genetic material. Using a full-genome RNA interference screen of Drosophila S2 cells, we identified about 200 genes that contribute to spin...

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Bibliografiske detaljer
Main Authors: Goshima, Gohta, Wollman, Roy, Goodwin, Sarah S., Zhang, Nan, Scholey, Jonathan M., Vale, Ronald D., Stuurman, Nico
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837481/
https://ncbi.nlm.nih.gov/pubmed/17412918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1141314
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